AUTONOMOUS INHIBITION OF APOPTOSIS CORRELATES WITH RESPONSIVENESS OF COLON CARCINOMA CELL LINES TO CIGLITAZONE.

Autonomous inhibition of apoptosis correlates with responsiveness of colon carcinoma cell lines to ciglitazone.

Colorectal cancer is a leading cause of mortality worldwide.Resistance to therapy is common and often results in patients succumbing to the cereal box disease.The mechanisms of resistance are poorly understood.Cells basically have two possibilities to survive a treatment with potentially apoptosis-inducing substances.They can make use of their exis

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New evidence from high-resolution computed microtomography of Triassic stem-mammal skulls from South America enhances discussions on turbinates before the origin of Mammaliaformes

Abstract The nasal cavity of living mammals AHCC is a unique structural complex among tetrapods, acquired along a series of major morphological transformations that occurred mainly during the Mesozoic Era, within the Synapsida clade.Particularly, non-mammaliaform cynodonts document several morphological changes in the skull, during the Triassic Per

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Urbanonymic Terminology: Systems and Problems

The article is focused on the problem of ordering and adaptation of modern Russian onomastic terminology to its foreign, especially Western European versions.The material for the analysis was the terms and their definitions from the Dictionary of Russian Onomastic Terminology by N.V.Podolskaya, the list of basic terms of ICOS (International Council

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Transfer of immunoglobulins through the mammary endothelium and epithelium and in the local lymph node of cows during the initial response after intramammary challenge with E. coli endotoxin

Abstract Background The first hours after antigen stimulation, interactions occur influencing the outcome of the immunological reaction.Immunoglobulins originate in blood and/or are locally synthesized.The transfer of Ig isotypes (Igs) in the udder has been studied previously but without the possibility to distinguish between the endothelium and th

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